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Table 1 Characteristics of the newborn patients with sepsis in the present study

From: miRNA-23b as a biomarker of culture-positive neonatal sepsis

EOS/LOS

(n = 27, 21)

Full-term patients

Premature patients

p

Co/NH (control)

(9, 6)

SP/PH

(7, 12)

DP/PH

(2, 1)

DP/NH

(0, 2)

Co/NH (control)

(4, 0)

SP/PH

(2, 0)

DP/PH

(3, 0)

Gender (M/F)

 EOS

5/4

4/3

1/1

1/3

1/1

2/1

NS

 LOS

6/0

6/6

0/1

2/0

NS

Weight (kg)

 EOS

2.87 ± 0.76

3.16 ± 0.65

3.30 ± 0.14

2.01 ± 0.09

1.43 ± 0.23

1.63 ± 0.57

< 0.001

 LOS

3.17 ± 0.86

3 ± 0.86

2.5 ± 0

2.9 ± 0.28

< 0.001

T (° C)

 EOS

36.17 ± 1.43

35.05 ± 1.42

34.5 ± 1.27

36.35 ± 2.30

33.07 ± 2.21

36.17 ± 1.20

NS

 LOS

37.33 ± 2.85

38.3 ± 1.53

37.4 ± 0

39.05 ± 0.95

NS

HR (BPM)

   

    

 EOS

136 ± 16.37

143.6 ± 17.87

125 ± 9.9

120.5 ± 19.58

125 ± 7.07

150 ± 10

NS

 LOS

151.8 ± 27

140.3 ± 17.27

180 ± 0

135 ± 7.07

NS

RR (BrPM)

   

    

 EOS

55.3 ± 14.56

55.7 ± 17.1

38 ± 5.66

 

58 ± 5.42

42 ± 2.83

62.67 ± 4.72

NS

 LOS

50.7 ± 14.01

52.5 ± 6.1

52 ± 0

42 ± 2.83

NS

Gly (mg/dL)

 EOS

0.95 ± 0.48

0.63 ± 0.23

0.52 ± 0.60

 

0.73 ± 0.25

0.45 ± 0.15

NS

 LOS

1.12 ± 0.22

0.65 ± 0.21

0.66 ± 0.17

NS

CRP (mg/dL)

 EOS

25.78 ± 17.87

41.17 ± 30.75

63 ± 88.25

< 0.0001

 LOS

47 ± 81.37

39.87 ± 29.78

42 ± 25.45

NS

VD vs. CD

   

  

 

 EOS

5/4

5/2

1/1

2/2

1/1

1/2

NS

 LOS

5/1

1/1

1/0

2/0

NS

  1. Data are presented as the mean ± standard deviation (X ± SD)
  2. BPM beats per minute, BrPM breaths per minute, CF Cardiac frequency, Co/ NH control newborns with negative haemoculture, CRP C-reactive protein, DP/NH patients who died with negative haemoculture, DP/PH patients who died with positive haemoculture, EOS early onset sepsis, F female, Gly glycaemia, HR Heart rate, EOS early onset sepsis, LOS late onset sepsis, M male, NS not significant, RR Respiratory rate, SP/PH patients who survived with positive haemoculture, VD vs. CD vaginal vs. caesarean delivery