Fig. 1
From: Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression
Human KBTBD8 was overexpressed in multiple clinical ovarian cancer samples. a KBTBD8 immunohistochemistry on an ovary tissue microarray showed that KBTBD8 level was highly correlated with the malignancy grade of ovarian cancer (Detailed information for each array point is in Additional file 1: Dataset 1). The malignancy grade and corresponding percentage of cells with high-level KBTBD8 are: 0 (0), 1 (60%), 2 (70%), and 3 (100%). b, c Western blot and quantification showed that the KBTBD8 protein level in ovarian cancer tissue was about fourfold higher than in adjacent normal ovarian tissue (Adjacent normal ovarian tissue vs. ovarian cancer tissue, 0.02689 vs. 0.1190). A.U., arbitrary unit. Scale bar, 100 μm. ***Indicates p < 0.001