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Fig. 4 | Molecular Medicine

Fig. 4

From: Silencing long non-coding RNA XIST suppresses drug resistance in acute myeloid leukemia through down-regulation of MYC by elevating microRNA-29a expression

Fig. 4

Down-regulated XIST enhanced apoptosis and slowed down cell cycle progression in KG-1 cells via MYC down-regulation. a The apoptosis of KG-1 cells detected by flow cytometry. b The cell cycle distribution of KG-1 cells examined by flow cytometry. c, d The expression of apoptosis-related genes (Bcl-2, Bax and Cleaved-caspase-3) in KG-1 cells determined by Western blot analysis. *p < 0.05 vs. KG-1 cells without any treatment. The data were measurement data, and expressed as mean ± standard deviation. Data comparison among multiple groups was conducted by one-way ANOVA. The experiment was repeated 3 times independently

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Molecular Medicine

ISSN: 1528-3658