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Fig. 6 | Molecular Medicine

Fig. 6

From: Silencing long non-coding RNA XIST suppresses drug resistance in acute myeloid leukemia through down-regulation of MYC by elevating microRNA-29a expression

Fig. 6

The molecular mechanisms illustrating the effect of the XIST/miR-29a/MYC axis on viability, apoptosis and drug resistance of AML cells. XIST can competitively bind to miR-29a to down-regulate miR-29a expression and up-regulate MYC expression, thereby increasing drug resistance and suppressing the apoptosis of AML cells

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Molecular Medicine

ISSN: 1528-3658