Skip to main content

Table 2 Laboratory findings of 74 severe and critically ill patients

From: IP-10 and MCP-1 as biomarkers associated with disease severity of COVID-19

Laboratory findings

Total (N = 74)

Severe patients (N = 19)

Critically ill patients (N = 55)

P

n

Median (IQR)

n

Median (IQR)

n

Median (IQR)

ELISA

 IP-10, pg/mL

74

364.8 (203.7–939.4)

19

193.1 (123.0–300.5)

55

531.3 (278.0–1217.3)

 < 0.001

 MCP-1, pg/mL

73

642.2 (293.2–1207.5)

18

230.7 (137.9–338.7)

55

837.0 (425.6–1374.0)

 < 0.001

 MIP1a, pg/mL

74

28.6 (15.2–79.7)

19

25.5 (13.8–86.1)

55

30.6 (16.4–77.6)

0.338

Cytokines

 IL-1β, pg/mL

29

5.0 (5.0–5.0)

4

5.0 (5.0–5.0)

25

5.0 (5.0–5.9)

0.284

 IL-2R, U/mL

30

1055.5 (464.5–1609.5)

5

740.0 (325.0–1314.5)

25

1258.0 (518.5–1820.0)

0.331

 IL-6, pg/mL

48

74.2 (17.0–157.5)

13

10.4 (5.4–31.1)

35

103.0 (43.0–323.2)

 < 0.001

 IL-8, pg/mL

29

51.7 (12.5–114.7)

4

11.1 (8.1–60.8)

25

62.3 (19.9–142.5)

0.077

 IL-10, pg/mL

29

11.4 (5.0–20.1)

4

5.0 (5.0–8.0)

25

11.9 (5.0–25.1)

0.049

 TNFα, pg/mL

27

12.7 (7.5–28.7)

4

7.8 (6.4–9.1)

23

13.3 (7.5–30.3)

0.414

Hematologic parameters

 Platelets, × 109/mL

72

132.5 (70.8–232.0)

17

254.0 (158.5–370.5)

55

88.0 (56.0–191.0)

 < 0.001

 Platelet distribution width (PDW), fL

64

14.4 (12.9–16.6)

17

13.4 (11.5–14.4)

47

14.5 (13.1–18.6)

 < 0.001

 Mean platelet volume (MPV), fL

64

11.6 (11.0–12.6)

17

11.2 (10.3–11.7)

47

11.9 (11.2–13.1)

0.005

 Platelet larger cell ratio (P-LCR), %

64

37.9 (33.1–45.2)

17

33.2 (26.9–38.2)

47

40.3 (34.2–47.6)

0.003

 Plateletcrit (PCT), %

64

0.19 (0.10–0.26)

17

0.28 (0.19–0.37)

47

0.13 (0.08–0.23)

 < 0.001

Coagulation function

 Prothrombin time (PT), s

71

15.9 (14.9–18.2)

17

14.9 (14.0–15.6)

54

16.9 (15.5–18.5)

 < 0.001

 Prothrombin activity (PTA), %

71

69.0 (55.0–80.0)

17

80.0 (72.5–89.0)

54

63.0 (53.3–72.5)

 < 0.001

 International normalized ratio (INR)

71

1.26 (1.15–1.49)

17

1.15 (1.07–1.23)

54

1.36 (1.22–1.54)

 < 0.001

 Fibrinogen (FIB), g/L

71

4.2 (3.1–5.2)

17

4.2 (3.5–4.9)

54

4.2 (3.0–5.3)

0.845

 Activated partial thromboplastin time (APTT), s

71

44.5 (39.3–52.6)

17

41.5 (37.0–46.6)

54

46.4 (40.7–53.9)

0.089

 Thrombin time (TT), s

71

15.3 (14.5–16.5)

17

15.0 (14.3–15.7)

54

15.5 (14.7–16.9)

0.083

 d-dimer, μg/mL FEU

71

3.9 (1.7–13.5)

17

2.4 (1.3–3.6)

54

6.2 (2.3–15.2)

0.006

 Fibrin degradation products (FDP), μg/mL

30

17.2 (6.2–68.6)

6

4.9 (4.0–7.8)

24

33.6 (13.6–102.6)

0.003

 Antithrombin (AT), %

34

80.5 (65.5–88.5)

8

85.0 (74.3–93.0)

26

78.5 (63.0–86.5)

0.219

  1. Bold indicates the statistically significant values (P < 0.05)