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Fig. 5 | Molecular Medicine

Fig. 5

From: Electroacupuncture reduces scopolamine-induced amnesia via mediating the miR-210/SIN3A and miR-183/SIN3A signaling pathway

Fig. 5

The inhibited mRNA and protein expression of Arc, Egr1, Homer1 and Narp in the hippocampus of SIA rats was up-regulated by EA treatment (a Real-time PCR; b Western blot; Technical repeats n = 3; Animal number in each group N = 6; *p value < 0.05, vs. sham group; **p value < 0.05, vs. SIA group). a Compared with the sham-operated rats, the gene expression of Arc mRNA was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above genes. b Compared with the sham-operated rats, the gene expression of Egr1 mRNA was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above genes. c Compared with the sham-operated rats, the gene expression of Homer1 mRNA was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above genes. d Compared with the sham-operated rats, the gene expression of Narp mRNA was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above genes. e Compared with the sham-operated rats, the protein expression of Arc was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above proteins. f Compared with the sham-operated rats, the protein expression of Egr1 was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above proteins. g Compared with the sham-operated rats, the protein expression of Homer1 was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above proteins. h Compared with the sham-operated rats, the protein expression of Narp was decreased in the hippocampus of SIA rats, and EA treatment partly restored the decreased expression of above proteins. i Western blot of the protein expression of Arc, Egr1, Homer1 and Narp of all rat groups

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