Fig. 3

PTEN inhibitor reduced cardiomyocytic apoptosis in MI mice. a Western blot was used to detect the protein levels of Bcl2, Caspase 9, Caspase 7 and Caspase 3 the peri-infarct area of the heart 14 days after MI. b, c Representative TUNEL and α-actinin staining of cardiomyocytes in cardiac sections from different groups. Green color in TUNEL staining was apoptotic cells; red color represented α-actinin, which is the marker of cardiomyocytes; DAPI stained blue color was the nucleus. Scale bar = 50 μm. n = 8. Data were represented as means ± SEM. **p < 0.01, ***p < 0.001, ns no significant difference