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Fig. 5 | Molecular Medicine

Fig. 5

From: MiR-128-3p inhibits vascular smooth muscle cell proliferation and migration by repressing FOXO4/MMP9 signaling pathway

Fig. 5

The effects of FOXO4 and MMP9 on miR-128-3p function. a The expressions of FOXO4 and MMP9 were detected by Western blot after transfection. b–e The quantification of FOXO4 and MMP9 at the mRNA and protein levels in VSMCs after transfection. The levels of inflammatory factors TNF-α (f), IL-1β (g) and IL-6 (h) in supernatants of VSMCs were examined by ELISA. i, j The proliferation of VSMCs was detected by CCK-8. k The proliferation of VSMCs was examined by BrdU assay. l The migration of VSMCs was examined by Transwell assay. m The apoptosis of VSMCs was examined by flow cytometry. *, **, *** represent p < 0.05, p < 0.01, p < 0.001, respectively

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Molecular Medicine

ISSN: 1528-3658