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Fig. 2 | Molecular Medicine

Fig. 2

From: Targeting the eCIRP/TREM-1 interaction with a small molecule inhibitor improves cardiac dysfunction in neonatal sepsis

Fig. 2

Treatment with M3 reduces proinflammatory cytokines in neonatal sepsis. 16 h after CS injection, serum from sham, vehicle, or M3 treated pups was collected to measure serum cytokines a IL-6, b IL-1β, c TNF-⍺, and d IFN-γ by ELISA. Data are expressed as means ± SE (sham = 8, vehicle = 6, and M3 = 7 pups). Multiple groups were compared by one-way ANOVA and Tukey method (*p < 0.05 vs. sham; #p < 0.05 vs. Vehicle)

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