Fig. 5From: Targeting the eCIRP/TREM-1 interaction with a small molecule inhibitor improves cardiac dysfunction in neonatal sepsisM3 improves survival in neonatal murine sepsis. Mouse pups were injected with a reduced dose of cecal slurry (0.175 mg/g BW) and treated with either M3 or normal saline vehicle. The square black line represents M3 treatment at the time of cecal slurry injection. The triangle blue line represents M3 treatment 2 h after sepsis injection. N = 13 mice per group, *p < 0.05 vs. vehicle, determined by the log-rank testBack to article page