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Fig. 8 | Molecular Medicine

Fig. 8

From: Targeting the eCIRP/TREM-1 interaction with a small molecule inhibitor improves cardiac dysfunction in neonatal sepsis

Fig. 8

rmCIRP impairs cardiac strain. In vivo rmCIRP exposures causes cardiac dysfunction as evidenced by changes in global longitudinal and radial strain and strain rate. 2 h after rmCIRP injection, mouse pups underwent echocardiogram. B modes images were analyzed using VivoStrain software. rmCIRP injection resulted in impaired a longitudinal strain and b strain rate as well as impaired c radial strain and d strain rate. Data are expressed as means ± SE and compared by two-tailed student’s t test (* p < 0.05 vs PBS control; PBS = 9, rmCIRP = 10)

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Molecular Medicine

ISSN: 1528-3658