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Table 1 List of significantly changed proteins from 2D-DIGE identified by MS (p < 0.05, minimum 1.5-fold change)

From: Variant in NHLRC2 leads to increased hnRNP C2 in developing neurons and the hippocampus of a mouse model of FINCA disease

Spot

Protein

Description

Ratio

t-Test

1

VCP

Transitional endoplasmic reticulum ATPase

− 2.07

0.01

2

ANXA6

Annexin A6

1.85

0.04

3

PLS3

Plastin-3

1.62

0.05

4

SNX6

Sorting nexin-6

1.62

0.02

5

hnRNP C1/C2

Heterogeneous nuclear ribonucleoprotein C1/C2 (isoform C2)

1.54

0.03

6

UBL7

Ubiquitin-like protein 7

1.95

0.04

7

GPD1L

Glycerol-3-phosphate dehydrogenase 1-like protein (isoform 1 or 2)

1.54

0.03

8

TIMM29

Mitochondrial import inner membrane translocase subunit Tim29

1.57

0.03

9

UBA1

Ubiquitin-like modifier-activating enzyme 1 (C-terminal fragment)

2.45

0.04

10

PRDX6

Peroxiredoxin-6

1.90

0.01

11

PSMA2

Proteasome subunit α type-2

1.66

0.04

12

FTL1

Ferritin light chain 1

1.77

0.04

13

RBM8A

RNA-binding protein 8A (isoform 1)

1.60

0.05

14

FTL1

Ferritin light chain 1 (N-terminal fragment)

2.14

0.02

15

PFDN2

Prefoldin subunit 2

1.68

0.05

16

HIST1H4A

Histone H4

1.62

0.03

17

HIST1H4A

Histone H4

2.89

0.03

18

DYNLRB1

Dynein light chain roadblock-type 1

1.68

0.04

19

ABRACL

Costars family protein ABRACL

1.63

0.04

20

PEA15

Astrocytic phosphoprotein PEA-15 (isoform 1)

2.04

0.04

21

BRK1

Protein BRICK1

1.81

0.03

  1. The ratio indicates the change of the normalized spot volumes in Nhlrc2FINCA/− in comparison to Nhlrc2+/+ NPCs