Table 1 Study cohort clinical characteristics
From: Genomic imbalances in the placenta are associated with poor fetal growth
Group | Gestational age at birth (w), mean (range) | Maternal age at birth (y), mean (range) | Sex, N male (%) | Birthweight (S.D.), mean (range) | Twins, N (%) | PE, N (%) |
|---|---|---|---|---|---|---|
Vancouver cohort—total samples | ||||||
 Control (N = 136) | 39.2 (30.1–41.9) | 34.3 (23.8–45.8) | 68 (50) | 0.1 (− 1.2 to 2.7) | 11 (8) | 0 (0) |
 SGA (N = 71) | 35.3 (23.6–41.7)* | 35.2 (23.1–41.0) | 34 (48) | − 1.9 (− 3.6 to − 1.2)* | 12 (17) | 31 (44) |
Subset of samples for CNV profiling | Â | |||||
 Control (N = 24) | 39.3 (38.0–41.4) | 34.8 (30.2–40.5) | 13 (54) | 0.01 (− 1.1 to 2.2) | 0 (0) | 0 (0) |
 SGA (N = 29) | 34.9 (24.0–40.6)* | 34.4 (23.9–42.9) | 18 (62) | − 1.9 (− 3.0 to − 0.6)* | 0 (0) | 11 (38) |
Toronto cohort—total samples | ||||||
 Control (N = 37) | 37.1 (27.3–41.0) | 32.9 (21–43) | 19 (51) | 0.28 (− 1.1–1.5) | 0 (0) | 0 (0) |
 SGA (N = 30) | 34.0 (27.1–38.6)* | 35.1 (25–44) | 9 (30) | − 2.2 (− 3.5–1.2)* | 5 (17)* | 0 (0) |