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Table 1 Study cohort clinical characteristics

From: Genomic imbalances in the placenta are associated with poor fetal growth

Group Gestational age at birth (w), mean (range) Maternal age at birth (y), mean (range) Sex, N male (%) Birthweight (S.D.), mean (range) Twins, N (%) PE, N (%)
Vancouver cohort—total samples
 Control (N = 136) 39.2 (30.1–41.9) 34.3 (23.8–45.8) 68 (50) 0.1 (− 1.2 to 2.7) 11 (8) 0 (0)
 SGA (N = 71) 35.3 (23.6–41.7)* 35.2 (23.1–41.0) 34 (48) − 1.9 (− 3.6 to − 1.2)* 12 (17) 31 (44)
Subset of samples for CNV profiling  
 Control (N = 24) 39.3 (38.0–41.4) 34.8 (30.2–40.5) 13 (54) 0.01 (− 1.1 to 2.2) 0 (0) 0 (0)
 SGA (N = 29) 34.9 (24.0–40.6)* 34.4 (23.9–42.9) 18 (62) − 1.9 (− 3.0 to − 0.6)* 0 (0) 11 (38)
Toronto cohort—total samples
 Control (N = 37) 37.1 (27.3–41.0) 32.9 (21–43) 19 (51) 0.28 (− 1.1–1.5) 0 (0) 0 (0)
 SGA (N = 30) 34.0 (27.1–38.6)* 35.1 (25–44) 9 (30) − 2.2 (− 3.5–1.2)* 5 (17)* 0 (0)
  1. SGA small-for-gestational age, PE preeclampsia
  2. *p < 0.05, p-values calculated in comparison to respective control groups by Student’s t-test for maternal age and birth weight, Mann–Whitney U-test for gestational age, and Fisher’s exact test for all categorical variables