Table 3 Summary of load of CNVs in control and SGA placentas
From: Genomic imbalances in the placenta are associated with poor fetal growth
| Â | Vancouver cohort | Toronto cohort | ||
|---|---|---|---|---|
|  | Control (N = 24) | SGAa (N = 28) | Control (N = 37) | SGA (N = 25) |
N CNVs | 17 (11–25) | 16 (9–27) | 35 (20–57) | 32 (22–52) |
 Gains | 7 (1–11) | 7 (1–14) | 17 (9–38) | 15 (8–36) |
 Losses | 10 (4–20) | 9 (3–17) | 18 (9–33) | 17 (10–29) |
N rare CNVs | 4 (1–10) | 4 (2–10) | 7 (1–29) | 6 (1–19) |
 Gains | 1 (0–6) | 2 (0–6) | 4 (0–22) | 3 (0–16) |
 Losses | 3 (0–7) | 3 (0–9) | 3 (0–12) | 3 (0–6) |
Cumul. size (Mb) | 1.22 (0.44–3.43) | 1.59 (0.57–5.12) | 3.20 (1.25–7.86) | 3.17 (1.63–5.80) |
 Gains | 0.57 (0.03–1.32) | 0.86 (0.03–2.85) | 2.36 (1.06–6.97) | 2.05 (0.97–5.11) |
 Losses | 0.65 (0.06–2.92) | 0.72 (0.11–3.45) | 0.84 (0.18–2.33) | 1.12 (0.36–4.19) |
Cumul. size rare (kb) | 219 (10–902) | 327 (74–864)* | 893 (38–3652) | 825 (19–3329) |
 Gains | 100 (0–781) | 197 (0–819) | 678 (0–3460) | 516 (0–2937) |
 Losses | 119 (0–485) | 130 (0–517) | 1570 (0–5776) | 1373 (0–4516) |