Fig. 2
From: Escape from X chromosome inactivation and female bias of autoimmune diseases
A schematic diagram of contribution of escape genes to the female bias of autoimmune diseases. Prone females can express the escape genes in double doses compared to males due to its expression from two X chromosome. CD40L: Cluster of differentiation 40 ligand; CD99: Cluster of differentiation 99; CXORF21: Chromosome X open reading frame 21; IRAK-1: Interleukin-1 receptor-associated kinase-1; XIAP: X-linked inhibitor of apoptosis protein; TLR7: Toll-like receptor 7; USP27X: Ubiquitin carboxyl-terminal hydrolase 27