Fig. 6From: Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant gliomaMTCH2 knockdown increases temozolomide-induced apoptosis of glioma cells. a, b Images (a) and quantifications (b) of Hoechst staining showing that MTCH2 knockdown promotes cell apoptosis of A172 cells after temozolomide treatment (200 μM, 48 h) (N = 3). Scale bar, 20 μm. c, d Images (c) and quantifications (d) of flow cytometry showing that MTCH2 knockdown promotes apoptosis of A172 cells after temozolomide treatment (200 μM, 48 h) (N = 3). e, f Western blots (e) and quantifications (f) showing that MTCH2 knockdown alters cellular signalings relative to cell survival/death (N = 4)Back to article page