The association of CASC16 variants with breast Cancer risk in a northwest Chinese female population

Table 2 The distribution of allele frequencies of CASC16 SNPs in case and control

SNP ID	Alleles (minor/major)	Chromosome position	MAF		O (HET)	E (HET)	p^a-HWE	OR (95% CI)	p^b
SNP ID	Alleles (minor/major)	Chromosome position	Case	Control	O (HET)	E (HET)	p^a-HWE	OR (95% CI)	p^b
rs3803662	G/A	chr16: 52552429	0.307	0.328	0.430	0.441	0.542	0.91 (0.77–1.06)	0.228
rs4784227	T/C	chr16: 52565276	0.277	0.239	0.356	0.363	0.596	1.22 (1.03–1.45)	0.022
rs45544231	C/G	chr16: 52598818	0.197	0.193	0.302	0.312	0.389	1.02 (0.85–1.24)	0.824
rs12922061	T/C	chr16: 52601088	0.285	0.247	0.385	0.372	0.410	1.21 (1.02–1.44)	0.026
rs3112612	G/A	chr16: 52601252	0.197	0.195	0.299	0.314	0.221	1.01 (0.84–1.23)	0.885

SNP single nucleotide polymorphisms, MAF minor allele frequency, HWE Hardy–Weinberg equilibrium
p^a values were calculated by exact test, p^a < 0.05 are excluded
p^b values were calculated by two–sided χ², p^b < 0.05 indicates statistical significance

ISSN: 1528-3658