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Table 2 Clinicopathological variables of 104 CRC patients and their correlation with PI3K (p110α) expression

From: Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

VariablesAll cases (N = 104; %)Negative (N = 31; %)Positive (N = 73; %)P-values
Male67 (64.4%)18 (26.9%)49 (73.1%)0.382
Female37 (35.6%)13 (35.1%)24 (64.9%) 
≤6566 (63.5%)21 (31.8%)45 (68.2%)0.658
≥6538 (36.5%)10 (26.3%)28 (73.7%) 
M073 (70.2%)27 (37.0%)46 (63.0%)0.018
M131 (29.8%)4 (12.9%)27 (87.1%) 
PIK3CA wild-type67 (64.4%)28 (41.8%)39 (58.2%)< 0.001
PIK3CA mutant37 (35.6%)3 (8.1%)34 (91.9%)