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Fig. 1 | Molecular Medicine

Fig. 1

From: Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose

Fig. 1

Increase in mammalian sterile 20-like kinase 1 (MST1) in the cardiomyocytes of diabetic offspring in vivo. a Immunostaining of MST1 in the myocardium of normal and diabetes-exposed embryos at E15.5 (n = 3). Scale bar: 50 µm. b Western blotting with the indicated antibodies in the diabetes and non-diabetes groups (n = 8 each) confirmed the increase in MST1 protein in heart tissues. β-Actin was used as an internal reference control. Western blotting of MST protein (c) and real-time PCR of MST1 mRNA expression (d) in cardiomyocytes after 2 days of high glucose (HG) treatment. Data are based on three independent experiments

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