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Fig. 4 | Molecular Medicine

Fig. 4

From: Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose

Fig. 4

Down-expression of YAP1 are associated with MST1-mediated cardiomyocyte apoptosis. a The decrease YAP1 protein level in response to HG was remarkably suppressed when H9C2 cells were transfected with MST1 siRNA for western blotting. b Western blotting estimated of the protein level of YAP1 after transfection with MST1 expression plasmid. c Western blotting confirmation of the ectopic expression of YAP1 in H9C2 cells after transfection with YAP1 expression plasmid. d Over-expression of YAP1 suppressed the increase apoptotic rate in H9C2 cells, which was mediated by MST1 induced by HG

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