Fig. 7

Combination of vanoxerinedihydrochloride and 5-FU produced synergistic cytotoxic effects in Huh7 cells. Huh7 cells were seeded in 96-well plates, and treated with indicated concentrations of vanoxerine dihydrochloride and 5-Fu. a Cell viability was detected by CCK8 after 72 h treatment. b The combined effect was analyzed by CompuSyn software analysis of the Combination Index (CI) of the combined action. c A dot plot of the combined action of vanoxerine dihydrochloride and 5-Fu