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Fig. 3 | Molecular Medicine

Fig. 3

From: ELAVL1 is transcriptionally activated by FOXC1 and promotes ferroptosis in myocardial ischemia/reperfusion injury by regulating autophagy

Fig. 3

ELAVL1 regulates H/R induced autophagy. Myocardial cells were transfected with si-ELAVL1 or si-NC and then subjected to H/R. a Relative mRNA levels of Beclin-1, p62 and LC3 were detected by qRT-PCR. b, c Western blotting was allowed to assess relative protein levels of Beclin-1, p62 and LC3 in transfected cells following H/R. d, e Immunostaining analysis of cellular LC3 levels in transfected cells following H/R. The results were presented as the mean ± SD. n = 3; *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Medicine

ISSN: 1528-3658