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Fig. 4 | Molecular Medicine

Fig. 4

From: Long non-coding RNA CIR inhibits chondrogenic differentiation of mesenchymal stem cells by epigenetically suppressing ATOH8 via methyltransferase EZH2

Fig. 4

LncRNA CIR directly binds to EZH2. a qRT-PCR analysis of lncRNA CIR level in cytoplasm and nucleus. b RIP assay was performed to analyze lncRNA CIR/EZH2 interaction. c Biotin-RNA pull down assay was used to measure the interactions of lncRNA CIR with EZH2 and H3K27me3. n = 3; *P < 0.05; **P < 0.01; ***P < 0.001

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