Fig. 5

Effects of overexpression of circROBO2 on myocardial function. a Relative expression levels of circROBO2, miR-1184 and TRADD mRNA in mice group of sham, MI, si-circROBO2 transfection, miR-1184 transfection and miR-1184 + circROBO2 transfection. b TRADD protein expression levels. LVEF (c), LVFS (d), Expression of LVESd (e) and LVEDd (f) in Sham, MI, si-circROBO2, miR-1184, and si-circROBO2 + miR-1184 groups. Myocardial cells were from three individual mice. * vs normoxic control group, # vs NC group and vs circROBO2 group. ***P < 0.001, ^##P < 0.01 and ^&P < 0.05