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Fig. 2 | Molecular Medicine

Fig. 2

From: Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition

Fig. 2

CC16 suppresses HDM-induced airway epithelial apoptosis in mice. a Representative staining for TUNEL images from airway epithelial tissues of each group (magnification at × 200 and × 400). b Quantitative assessment of the percentage of TUNEL-positive cells in 5 random areas for each section. Red arrows indicated apoptotic airway epithelial cells. c Representative immunoblotting images of Bcl-2, Bax and cleaved caspase-3 expressions in lung tissues from each group. d Relative expression levels of above proteins was shown as bar graphs. Data are expressed as means ± SEM. ##p < 0.01 vs. Control group; *p < 0.05 vs. HDM group; **p < 0.01 vs. HDM group

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