Skip to main content
Fig. 4 | Molecular Medicine

Fig. 4

From: Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition

Fig. 4

CC16 treatment restrains HDM-induced upregulation of HMGB1 in vivo and in vitro. a Representative immunohistochemistry images of HMGB1 expression in airway epithelium after different treatments. Scale bar = 100 μm. b The BALF levels of HMGB1 were determined by ELISA among different groups. c Western blot was performed to examine HMGB1 expression in lung tissues of different groups. d Quantitation of the HMGB1/β-actin ratios. e Representative immunofluorescence images of HMGB1 (green) in BEAS-2B cells with different treatments. Scale bar = 100 μm. Data are expressed as means ± SEM. ##p < 0.01 vs. Control group; *p < 0.05 vs. HDM group; **p < 0.01 vs. HDM group

Back to article page

Molecular Medicine

ISSN: 1528-3658