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Fig. 5 | Molecular Medicine

Fig. 5

From: TGF-β-induced α-SMA expression is mediated by C/EBPβ acetylation in human alveolar epithelial cells

Fig. 5

Involvement of C/EBPβ acetylation in TGF-β-induced EMT in A549 cells. a Cell lysates were prepared from A549 cells treated with 10 ng/mL TGF-β for 24 h. After treatment with the C/EBPβ antibody (described in “Methods”), C/EBPβ acetylation was shown to be involved in TGF-β-induced α-SMA expression. b Quantification of western blots were calculated according to grey analysis. However, elevated expression of acetylated C/EBPβ and α-SMA proteins was not observed in A549 cells treated with IgG during immunoprecipitation. Data show mean ± SEM. Asterisk (*) denotes significant difference (P < 0.05) compared to the control

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