Table 1 Characteristics of study population and controls
Characteristics | Trauma patients (n = 136)a | Healthy controls (n = 20) |
|---|---|---|
Demographics | ||
Sex (male : female) | 101 : 35 | 11 : 9 |
Age (years) | 40 (18–94); n = 135 | 39 (22–58) |
Preinjury ASA PS (ASA I : II : III) | 85 : 37 :14 | |
Injuries | ||
Mechanism of injury (blunt : penetrating) | 118 : 18 | |
NISS | 27 (1–75) | |
ISS | 19 (1–75) | |
Serious injury (NISS ≥ 16; ISS ≥ 16) | 92; 80 | |
Critical injury (NISS ≥ 25; ISS ≥ 25) | 75; 57 | |
Major head injuryb (yes : no) | 59 : 77 | |
Admission BE (mmol/L) | –3.1 (–26.0–3.4); n = 127 | |
Admission BE ≤ –6 mmol/L (n) | 32 | |
TCC analyses | ||
Admission TCC (AU/mL) | 0.87 (0.08–14.1); n = 136 | 0.42 (0.08–1.52) |
TCC-AUC3 − 6 (AU/mL×h) | 2.49 (0.25–52.6); n = 120 | |
Time from injury to first sample (hours : minutes) | 1:15 (0:20–5:40) | |
Samples analysed per patient | 6 (1–35) | |
Mean interpolated TCC (AU/mL) | ||
Day 0 | 0.88 (0.17–15.1); n = 136 | |
Day 4 | 1.91 (0.08–12.7); n = 39 | |
Day 7 | 2.24 (0.72–15.2); n = 28 | |
Day 9 | 2.39 (0.53–21.4); n = 23 | |
Hospital treatment | ||
Transfused before ICU (yes : no : unknown) | 30 : 105 : 1 | |
Transfusions before ICU (PRBC units) | 9 (1–61); n = 30 | |
Hospital length of stay (days) | 6 (1–52) | |
ICU length of stay | 3 (1–52); n = 131 | |
SOFA score | ||
Day 0 | 6 (0–16); n = 133 | |
Day 4 | 9 (1–15); n = 39 | |
Day 7 | 9 (1–14); n = 26 | |
Day 9 | 9 (0–15); n = 20 | |
Ventilator treatment (yes : no) | 67 : 69 | |
Survival | ||
Dead at 30 days (yes : no) | 20 : 116 | |
Time to death (days) | 1 (0–23); n = 20 | |
Predefined outcome variable | ||
Ventilator–free days | 29 (0–30) | |