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Table 1 Characteristics of study population and controls

From: Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study

Characteristics Trauma patients (n = 136)a Healthy controls (n = 20)
Demographics
 Sex (male : female) 101 : 35 11 : 9
 Age (years) 40 (18–94); n = 135 39 (22–58)
 Preinjury ASA PS (ASA I : II : III) 85 : 37 :14  
Injuries
 Mechanism of injury (blunt : penetrating) 118 : 18  
 NISS 27 (1–75)  
 ISS 19 (1–75)  
 Serious injury (NISS ≥ 16; ISS ≥ 16) 92; 80  
 Critical injury (NISS ≥ 25; ISS ≥ 25) 75; 57  
 Major head injuryb (yes : no) 59 : 77  
 Admission BE (mmol/L) –3.1 (–26.0–3.4); n = 127  
 Admission BE ≤ –6 mmol/L (n) 32  
TCC analyses
 Admission TCC (AU/mL) 0.87 (0.08–14.1); n = 136 0.42 (0.08–1.52)
 TCC-AUC3 − 6 (AU/mL×h) 2.49 (0.25–52.6); n = 120  
 Time from injury to first sample (hours : minutes) 1:15 (0:20–5:40)  
 Samples analysed per patient 6 (1–35)  
Mean interpolated TCC (AU/mL)
 Day 0 0.88 (0.17–15.1); n = 136  
 Day 4 1.91 (0.08–12.7); n = 39  
 Day 7 2.24 (0.72–15.2); n = 28  
 Day 9 2.39 (0.53–21.4); n = 23  
Hospital treatment
 Transfused before ICU (yes : no : unknown) 30 : 105 : 1  
 Transfusions before ICU (PRBC units) 9 (1–61); n = 30  
 Hospital length of stay (days) 6 (1–52)  
 ICU length of stay 3 (1–52); n = 131  
SOFA score
 Day 0 6 (0–16); n = 133  
 Day 4 9 (1–15); n = 39  
 Day 7 9 (1–14); n = 26  
 Day 9 9 (0–15); n = 20  
 Ventilator treatment (yes : no) 67 : 69  
Survival
 Dead at 30 days (yes : no) 20 : 116  
 Time to death (days) 1 (0–23); n = 20  
Predefined outcome variable
 Ventilator–free days 29 (0–30)  
  1. Values are given as median and range unless otherwise stated
  2. a n is given where group size is < 136
  3. b Major head injury was defined as maximum Abbreviated Injury Scale (AIS) severity code ≥ 3 in ISS region Head or neck
  4. ASA PS American Society of Anesthesiologists Physical Status Classification System, NISS New Injury Severity Score, ISS Injury Severity Score, BE Base Excess, AU Arbitrary units, ICU Intensive Care Unit, PRBC Packed Red Blood Cells, SOFA score Sequential Organ Failure Assessment score