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Table 2 Pathological characteristics in two group of patients. Data are presented as proportion of individuals within each category

From: E2F1 copy number variations in germline and breast cancer: a retrospective study of 222 Italian women

  CNV = 2 CNV > 2 P value
Age at diagnosis (years) 60.4 ± 14.5 61.4 ± 13.6 0.74
Menopausal status 0.70
 Premenopausal 20.9% 10%
 Perimenopausal 3.7% 0.0%
 Menopausal 75.4% 90%
Estrogen receptor 0.84
 Positive 67.8% 80%
 Negative 32.2% 20%
Progesterone receptor 0.35
 Positive 53% 30%
 Negative 47% 70%
HER-2 status 0.99
 Positive 70.1% 70%
 Negative 29.9% 30%
Palpable tumour 0.07
 Yes 93.6% 70%
 No 6.4% 30%
Lymph node status 0.04*
 Negative 58.2% 80%
 Positive 41.8% 20%
Tumour type 0.93
 Invasive ductal carcinoma (IDC) 72.9% 80%
 Ductal carcinoma in situ (DCIS) 5.7% 0.0%
 Lobular 15.7% 20%
 D & L 1% 0.0%
 Other 2.9% 0.0%
Histological grade 0.36
 I 11.1% 0%
 II 51.9% 70%
 III 37% 30%
Location 0.04*
 Unilateral 95.5% 80%
 Bilateral 2.5% 20%
Familial history 0.001*
 Yes 45% 100%
 No 55% 0%
Size (cm) 0.64
 < 2 59% 60%
 > 2 41% 40%
Vascular invasion 0.21
 Yes 81% 0%
 No 19% 100%
  1. * p value < 0.05