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Fig. 2 | Molecular Medicine

Fig. 2

From: Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study

Fig. 2

Critically injured patients (NISS > 24) stratified according to absence (IL-33neg) or presence (IL-33pos) of detectable IL-33 at admission. Differences in a time after injury of first sample, b New Injury Severity Score (NISS), c Injury Severity Score (ISS), d number of ISS regions with injuries, eh maximum Abbreviated injury scale (AIS) severity score (with 0 representing no injury) in ISS regions Head or neck, Chest, Abdominal or pelvic contents, and Extremities or pelvic girdle, i activated partial thromboplastin time (aPTT) at admission, j international normalized ratio (INR) at admission, k units of packed red blood cells transfused prior to ICU admission, and l base excess at admission, are plotted and compared between the two groups. Black filled circles represent patients with blunt injuries, and red outlined circles represent patients with penetrating injuries. Statistical comparisons were performed with Kruskal–Wallis test with Dunn’s multiple comparison test on the patient groups, with both blunt and penetrating injuries included. Lines indicate median values. ns p ≥ 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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