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Table 2 RT-LAMP results testing 466 clinical samples stratified by Ct values

From: Essential properties and pitfalls of colorimetric Reverse Transcription Loop-mediated Isothermal Amplification as a point-of-care test for SARS-CoV-2 diagnosis

 

Positive

Positive

Negative

Low viral load

Ct < 30

Ct 30–35

Ct > 35

RTq-PCR

 Positive

93.8%

28.6%

5.2%

n = 150

n = 16

n = 13

 Negative

0.6%

39.3%

90.4%

n = 1

n = 22

n = 226

RT-LAMP

 Intermediate

5.6%

32.1%

4.4%

n = 9

n = 18

n = 11

 Total

34.3%

12.0%

53.6%

n = 160

n = 56

n = 250