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Fig. 3 | Molecular Medicine

Fig. 3

From: Circulating Tfh cell and subsets distribution are associated with low‐responsiveness to hepatitis B vaccination

Fig. 3

A skewed cTfh population away from cTfh2 and cTfh17 toward cTfh1 in low responder to the hepatitis B vaccine. a Representative dot plots of gating strategy for the analysis of CCR6 and CXCR3 expression in CXCR5+CD4+T cell or CXCR5CD4+T cell population. b Subset frequency in CXCR5+CD4+T cell or CXCR5CD4+T cell population between LR and HR at D7. c Comparison frequencies of Tfh1 cell, Tfh2 cell, Tfh17 cell between LR and HR at D7, D14 and D28. d Comparison ratio of (Tfh2 + Tfh17)/Tfh1 cell between LR and HR at D7, D14 and D28. e Kinetics of Tfh1 cell, Tfh2 cell and Tfh17 cell in LR and HR from D7 to D28. f Kinetics of ratio of (Tfh2 + Tfh17)/Tfh1 cell in LR and HR from D7 to D28. Median and range bars represent mean ± SD

LR low responders, HR hyper responders, D7 range 7–8 days after vaccination, D14 range 14–15 days after vaccination, D28 range 28–29 days after vaccination

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