Fig. 5

cTfh cells was associated with increased level of IL-21 and anti-HBs. a Comparison frequencies of IL-21 between LR and HR at D7, D14 and D28. b Kinetics of IL-21 and anti-HBs in LR and HR from D7 to D28. c Correlation analysis at D7 and D28. Median and range bars represent mean ± SD or median with interquartile range as appropriate
LR low responders, HR hyper responders, D7 range 7–8 days after vaccination, D14 range 14–15 days after vaccination, D28 range 28–29 days after vaccination