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Fig. 6 | Molecular Medicine

Fig. 6

From: Oscillatory shear stress promotes angiogenic effects in arteriovenous malformations endothelial cells

Fig. 6

Immunofluorescence for Angiopoietin2, Aquaporin1, and TGFβR1, Endothelial cells (Confocal). In Angiopoietin2 and TGFβR1, shear stress compared with neutral, protein expressions of cytoplasm increased in ECs both normal arterial vasculature and AVMs. Compared with normal arterial vasculature, protein expressions in AVMs increased under neutral and shear stress conditions. Regarding to Aquaporin1, shear stress compared with neutral, protein expressions in normal arterial vasculature increased. There were no significant differences in the degree of cytoplasmic fluorescence staining in endothelial cells from AVMs with and without shear stress application. Compared with normal arterial vasculature, protein expressions in AVMs were less than that observed in normal arterial vasculature under neutral or shear stress conditions. AVM Arteriovenous malformations; ECs endothelial cells

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Molecular Medicine

ISSN: 1528-3658