Oscillatory shear stress promotes angiogenic effects in arteriovenous malformations endothelial cells

Table 5 The values of relative quantity for gene expression in shear force and neutral environments; Comparison between AVMs and normal arterial vasculatures, types of environments were controlled

\(f(dCt)\)		AVMs (AGP2)	NA (AGP2)	AVMs (AQP1)	NA (AQP1)	AVMs (TGFβR1)	NA (TGFβR1)
NE	Mean	0.251	0.111	3.994	7.912	11.677	5.228
	SD	0.114	0.069	0.499	2.591	1.829	1.371
	RQ	2.265 (0.0278)*		0.505 (0.0132)*		2.234 (0.0000)***
	t	− 2.5716*		3.6374*		− 6.9119***
SF	Mean	1.278	0.181	1.658	8.313	29.074	13.373
	SD	0.319	0.052	0.400	2.985	9.836	1.852
	RQ	7.052 (0.0003)***		0.199 (0.0026)**		2.174 (0.0106)*
	t	− 8.3077***		5.4133**		− 3.8424*

AGP2 Angiopoietin2, AQP1 Aquaporin1, TGFβR1 tissue growth factor beta receptor1, AVMs Arteriovenous malformations, NA normal arterial vasculatures, NE neutral environments, SF Shear force state, SD standard deviation, RQ relative quantity \(RQ=\frac{avm.f(dCt)}{normal.f(dCt)}\)
*P < 0.05, **P < 0.01, ***P < 0.001

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