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Fig. 2 | Molecular Medicine

Fig. 2

From: Betacellulin regulates peripheral nerve regeneration by affecting Schwann cell migration and axon elongation

Fig. 2

The in vitro effect of siRNA against Btc on Schwann cell migration. a The transfection efficiency of siRNA-Btc. Relative abundance of Btc was summarized from three experiments. Statistical evaluation was performed using ANOVA. *p-value < 0.05 versus siRNA control. b Representative Transwell migration images and normalized averaged migration rate of Schwann cells transfected with siRNA control or siRNA-Btc. Scale bars represented 50 μm. Transwell migration assay was done three times using duplicate or triplicate wells. Statistical evaluation was performed using Mann–Whitney test. *p-value < 0.05 versus siRNA control. c Representative wound healing images and percentage decrease in scratch of Schwann cells transfected with siRNA control or siRNA-Btc. Scale bars represented 100 μm. Transwell migration assay was done four times using duplicate wells. Statistical evaluation was performed using Mann–Whitney test. *p-value < 0.05 versus siRNA control

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Molecular Medicine

ISSN: 1528-3658