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Fig. 2 | Molecular Medicine

Fig. 2

From: The emerging role of exosomal miRNAs as a diagnostic and therapeutic biomarker in Mycobacterium tuberculosis infection

Fig. 2

Schematic representation of exosome biogenesis, miRNA internalization, and release. The microRNA or miRNA genes are transcribed into pri-miRNAs (primary miRNAs) in the nucleus. In the next step, pri-miRNAs experiencing a further process by the Drosha complex to form pre-miRNAs (precursor miRNAs). The pre-miRNAs in the Dicer complex were digested to become mature miRNAs. Finally, the mature miRNAs are loaded into exosomes via various possible methods

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