Fig. 2From: The emerging role of exosomal miRNAs as a diagnostic and therapeutic biomarker in Mycobacterium tuberculosis infectionSchematic representation of exosome biogenesis, miRNA internalization, and release. The microRNA or miRNA genes are transcribed into pri-miRNAs (primary miRNAs) in the nucleus. In the next step, pri-miRNAs experiencing a further process by the Drosha complex to form pre-miRNAs (precursor miRNAs). The pre-miRNAs in the Dicer complex were digested to become mature miRNAs. Finally, the mature miRNAs are loaded into exosomes via various possible methodsBack to article page