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Fig. 2 | Molecular Medicine

Fig. 2

From: OTULIN is a new target of EA treatment in the alleviation of brain injury and glial cell activation via suppression of the NF-κB signalling pathway in acute ischaemic stroke rats

Fig. 2

EA enhanced OTULIN expression in ischaemic stroke rats. a A coronal brain section was stained with cresyl violet to show the analysed regions (*: ischaemic core area; □: the ischaemic penumbra of the cerebral cortex; the white dotted line separated the ipsilateral and contralateral cerebral hemisphere.). b OTULIN mRNA levels at each time point were detected using RT-qPCR (n = 3). c OTULIN protein levels in each group were examined using Western blotting. d The histogram presents the quantitative analysis of OTULIN protein (n = 3). e Immunofluorescence for OTULIN expression in the cortical penumbra was performed 48 h after reperfusion. Scale bar = 100 μm. f The histogram presents the quantitative analysis of OTULIN-positive cell counts (n = 8). ***P < 0.001, **P < 0.01, and *P < 0.05 versus the Sham group; &&&P < 0.001, &&P < 0.01, and &P < 0.05 versus the tMCAO group

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Molecular Medicine

ISSN: 1528-3658