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Table 3 Relationship between expression of ISL1-S629-p and clinic pathological parameters of gastric cancer

From: Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer

Characteristic

Expression Level of ISL1-S629-p

p-value

++(%)

+++(%)

(n = 29)

(n = 31)

Age

 ≤ 60

16 (55.2%)

10 (32.3%)

0.073

 > 60

13 (44.8%)

21 (67.7%)

Gender

 Male

19 (65.5%)

20 (64.5%)

0.935

 Female

10 (34.5%)

11 (35.5%)

Depth of invasion

 T1–2

12 (41.4%)

22 (71.0%)

0.021

 T3–4

17 (58.6%)

9 (29.0%)

Lymph node metastasis

 N0

10 (34.5%)

15 (48.4%)

0.275

 N1–3

19 (65.5%)

16 (51.6%)

Distant metastasis

 M0

25 (86.2%)

28 (90.3%)

0.702

 M1

4 (13.8%)

3 (9.7%)

TNM stage

 I

7 (24.1%)

14 (45.2%)

0.309

 II

10 (34.5%)

7 (22.6%)

 III

9 (31.0%)

6 (19.4%)

 IV

3 (10.3%)

4 (12.9%)

Histological grade*

 G1

1 (3.4%)

2 (6.5%)

0.010

 G2

6 (20.7%)

16 (51.6%)

 G3

22 (75.9%)

13 (41.9%)