Fig. 5

PRP inhibits doxorubicin-induced inflammation in SW1353. SW1353 were treated with PRP and doxorubicin for 24 h. A, B Western blot to detect protein levels of COX-2, iNOS, p-IκBα, IκBα, p-NF-κB 65, NF-κB 65, and β-actin. C mRNA levels of MMP-1, MMP-3, MMP-13, TNF-α, and IL-6. At least three independent experiments were performed. *p < 0.05 vs control of the same doxorubicin treatment; #p < 0.05 vs vehicle of the same TGFβ treatment