Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients

Table 2 Signal pathways involved in XRCC2 in glioma based on three datasets

Pathways	CGGA RNA-seq			CGGA microarray			TCGA RNA-seq
Pathways	NES	NOM P -value	FDR q-value	NES	NOM P -value	FDR q-value	NES	NOM P -value	FDR q-value
Cell cycle	1.950	0.000	0.123	1.983	0.004	0.021	2.239	0.000	0.001
DNA replication	1.715	0.029	0.146	1.966	0.000	0.017	2.048	0.000	0.005
Homologous recombination	1.572	0.046	0.178	2.046	0.000	0.015	2.024	0.002	0.004
Mismatch repair	1.715	0.008	0.159	1.797	0.015	0.105	2.076	0.000	0.004

NES normalized enrichment score, NOM nominal, FDR false discovery rate. Gene sets with NOM P-value < 0.05 and FDR q-value < 0.25 were considered as significantly enriched, NOM nominal, FDR false discovery rate.

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