Fig. 1
From: CircHYBID regulates hyaluronan metabolism in chondrocytes via hsa-miR-29b-3p/TGF-β1 axis
Proteoglycan of ECM and Hyaluronan (HA) accumulation was decreased in damaged cartilage. A Pathological examination and alcian blue staining of cartilage from intact and damaged areas (magnification × 100, scale bar 200 µm). The histological change was assessed using the Mankin score. B The Mankin score was significantly higher for damaged cartilage than for intact cartilage (Wilcoxon’s test, p < 0.0001). C The alcian blue staining score was significantly lower for damaged cartilage than for intact cartilage (Wilcoxon’s test, p < 0.0001). D Correlation scatter plot of the alcian blue score and the Mankin score (Pearson’s correlation, r = − 0.8665)