Fig. 5
From: CircHYBID regulates hyaluronan metabolism in chondrocytes via hsa-miR-29b-3p/TGF-β1 axis
CircHYBID elevated hyaluronan (HA) accumulation. The expression of circHYBID (A), HYBID (D), and HAS2 (F) were assessed using quantitative real-time polymerase chain reaction in IL-1β-induced chondrocytes with or without overexpressed circHYBID. IL-6 (B), TNF-α (C), and HA (E) levels in cell culture supernatant were measured using enzyme-linked immunosorbent assay. G The protein expression of HAS2 and HYBID was detected using Western blotting. *p < 0.01; **p < 0.01; ***p < 0.001; ****p < 0.0001