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Fig. 2 | Molecular Medicine

Fig. 2

From: MSCs‑derived exosomes attenuate ischemia-reperfusion brain injury and inhibit microglia apoptosis might via exosomal miR-26a-5p mediated suppression of CDK6

Fig. 2

MiR-26a-5p was downregulated and CDK6 was upregulated in MSCs-derived exosomes of MCAO and OGD model. A and B The mRNA expression of miR-26a-5p in MSCs-derived exosomes (A) and brain tissues (B) of MCAO-induced mice was evaluated by qRT-PCR. C The level of miR-26a-5p in exosomes of OGD-treated MSCs at indicated time was evaluated by qRT-PCR. D The protein expression of CDK6 in MSCs-derived exosomes of MCAO-induced mice was evaluated by western blot. E The protein expression of CDK6 in exosomes of OGD-treated MSCs at indicated time was evaluated by western blot. *p < 0.05, **p < 0.01

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