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Fig. 2 | Molecular Medicine

Fig. 2

From: CD36 deficiency ameliorates drug-induced acute liver injury in mice

Fig. 2

Lack of CD36 ameliorated liver inflammatory responses induced by APAP. The expression of A NAPQI-protein adducts and B CYP2E1 in the liver from WT and CD36−/− mice treated with APAP for 6 h. C mRNA level of cytokines was determined by RT-qPCR in the liver of WT and CD36−/− mice at 24 h after APAP treatment. D Serum IL-1β and IL-6 levels in WT and CD36−/− mice at 24 h after APAP overdosage. *P < 0.05, compared with WT mice. N = 5 mice per group

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