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Fig. 2 | Molecular Medicine

Fig. 2

From: Danshensu inhibits the IL-1β-induced inflammatory response in chondrocytes and osteoarthritis possibly via suppressing NF-κB signaling pathway

Fig. 2

DSS inhibited IL-1β-induced chondrocytes inflammation. The chondrocytes were pretreated with 2.5, 5, and 10 μM DSS for 24 h and stimulated with 10 ng/ml IL-1β for 2 h. A The mRNA levels of inflammation-related markers IL-6, COX-2, TNF-α, and iNOS were evaluated by qRT-PCR. B The protein levels of iNOS and COX-2 was detected by Western blot with β-actin as the internal reference. C The production of PGE2, TNF-α, NO, and IL-6 were detected by ELISA. **p < 0.01; ***p < 0.001

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