Fig. 5

Correlation between levels of IL-17A/GM-CSF and IL-17A/TNF in plasma and spleen of TLR4^−/− mice. Animals were injected with LPS (3 mg/kg, i.p.). At different time points upon sacrifice, the inflammatory mediators in blood and spleen were measured by Luminex™ as described in Materials and Methods. The plots show the Spearman’s correlations between levels of IL-17A/GM-CSF (A) and IL-17A/TNF (B) during the 0–12 h and 12–48 h time-intervals (the shaded area represents the 95% bootstrapped confidence interval)