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Fig. 1 | Molecular Medicine

Fig. 1

From: Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome

Fig. 1

MiR-135 is down-regulated and PCSK6 and NLRP3 is up-regulated in placenta tissues of PE patients. A HE staining of clinical placenta tissues (× 200); B TUNEL staining of clinical placenta tissues (× 200); C, D Detection of IL-1β and TNF-α levels in serum by ELISA; E Detection of miR-135-3p expression by qPCR; F. Detection of miR-135-5p expression by qPCR; G Detection of PCSK6 expression by qPCR; H Detection of NLRP3 expression by qPCR; I Detection of PCSK6 and NLRP3 protein expression by Western blot analysis; n = 25. *P < 0.05 vs. the control group

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