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Fig. 6 | Molecular Medicine

Fig. 6

From: Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway

Fig. 6

Simplified image displaying the results of the expression of hypoxia-induced Pref-1 through the ERK/PEA3/AP-1 pathway in human lung fibroblasts. Hypoxia induced the activation of ERK, which in turn caused PEA3 and AP-1 phosphorylation and complex formation. Moreover, PEA3 and AP-1 complex mediates Pref-1 expression through hypoxia stimulation in human lung fibroblasts

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