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Table 2 Associations between maternal glycemia and change in 13C-DHA lipids with in-vitro glucose treatment (glucose response) in placental explants (n = 17)

From: Placental 13C-DHA metabolism and relationship with maternal BMI, glycemia and birthweight

13C-DHA lipid Fasting glycemiaa Post load glycemia (2 h)a
Estimate (lower CI, upper CI)
Relative amountb/ (mmol/L)
p value (BH) Estimate (lower CI, upper CI)
Relative amountb/ (mmol/L)
p value (BH)
DG 38:6 0.106 (− 0.45, 0.663) 0.911 − 0.091 (− 0.241, 0.059) 0.216
DG 40:7 0.065 (− 0.542, 0.673) 0.822 − 0.108 (− 0.27 ,0.053) 0.172
DG 40:8 0.116 (− 0.506, 0.739) 0.919 − 0.093 (− 0.262, 0.076) 0.261
LPC 22:6 − 0.688 (− 1.732, 0.355) 0.18 − 0.228 (− 0.515, 0.059) 0.111
LPE 22:6 − 0.82 (− 2.092, 0.451) 0.189 − 0.26 (− 0.613, 0.093) 0.137
PC 38:6 − 0.474 (− 0.993, 0.046) 0.071 − 0.111 (− 0.264, 0.041) 0.139
PE-P 38:6 − 0.034 (− 0.45, 0.382) 0.912 − 0.079 (− 0.189, 0.03) 0.186
PE-P 40:6 − 0.196 (− 0.612, 0.219) 0.329 − 0.055 (− 0.172, 0.062) 0.338
TG 54:6 − 0.164 (− 0.741, 0.414) 0.555 − 0.075 (− 0.235, 0.085) 0.334
TG 54:7 − 0.123 (− 0.658, 0.413) 0.632 − 0.059 (− 0.208, 0.09) 0.412
TG 56:6 − 0.243 (− 0.823, 0.337) 0.387 − 0.06 (− 0.225, 0.105) 0.451
TG 56:7 − 0.128 (− 0.729, 0.474) 0.658 − 0.037 (− 0.207, 0.133) 0.65
TG 56:8 − 0.042 (− 0.647, 0.562) 0.883 − 0.053 (− 0.221, 0.115) 0.512
TG 56:9 − 0.256 (− 1.065, 0.553) 0.511 − 0.117 (− 0.34, 0.106) 0.28
TG 58:8 0.112 (− 0.398, 0.622) 0.89 − 0.01 (− 0.155, 0.135) 0.881
TG 58:9 − 0.086 (− 0.628, 0.457) 0.741 − 0.076 (− 0.224, 0.072) 0.289
TG 58:10 0.009 (− 0.649, 0.668) 0.976 − 0.052 (− 0.236, 0.132) 0.553
  1. CI confidence interval, BH Benjamini–Hochberg corrected
  2. aIn mid-gestation 75 g three time-point OGTT
  3. bChange in 13C-DHA lipid with glucose treatment or glucose response (log2-fold-change) represents the relative amount of 13C-DHA lipid in placental explants treated with glucose (10 mmol/L) compared to control explants from the same placenta. Positive values indicate an increase in 13C-DHA lipids compared to the control, whilst negative values indicate a decrease