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Table 2 Associations between maternal glycemia and change in 13C-DHA lipids with in-vitro glucose treatment (glucose response) in placental explants (n = 17)

From: Placental 13C-DHA metabolism and relationship with maternal BMI, glycemia and birthweight

13C-DHA lipid

Fasting glycemiaa

Post load glycemia (2 h)a

Estimate (lower CI, upper CI)

Relative amountb/ (mmol/L)

p value (BH)

Estimate (lower CI, upper CI)

Relative amountb/ (mmol/L)

p value (BH)

DG 38:6

0.106 (− 0.45, 0.663)

0.911

− 0.091 (− 0.241, 0.059)

0.216

DG 40:7

0.065 (− 0.542, 0.673)

0.822

− 0.108 (− 0.27 ,0.053)

0.172

DG 40:8

0.116 (− 0.506, 0.739)

0.919

− 0.093 (− 0.262, 0.076)

0.261

LPC 22:6

− 0.688 (− 1.732, 0.355)

0.18

− 0.228 (− 0.515, 0.059)

0.111

LPE 22:6

− 0.82 (− 2.092, 0.451)

0.189

− 0.26 (− 0.613, 0.093)

0.137

PC 38:6

− 0.474 (− 0.993, 0.046)

0.071

− 0.111 (− 0.264, 0.041)

0.139

PE-P 38:6

− 0.034 (− 0.45, 0.382)

0.912

− 0.079 (− 0.189, 0.03)

0.186

PE-P 40:6

− 0.196 (− 0.612, 0.219)

0.329

− 0.055 (− 0.172, 0.062)

0.338

TG 54:6

− 0.164 (− 0.741, 0.414)

0.555

− 0.075 (− 0.235, 0.085)

0.334

TG 54:7

− 0.123 (− 0.658, 0.413)

0.632

− 0.059 (− 0.208, 0.09)

0.412

TG 56:6

− 0.243 (− 0.823, 0.337)

0.387

− 0.06 (− 0.225, 0.105)

0.451

TG 56:7

− 0.128 (− 0.729, 0.474)

0.658

− 0.037 (− 0.207, 0.133)

0.65

TG 56:8

− 0.042 (− 0.647, 0.562)

0.883

− 0.053 (− 0.221, 0.115)

0.512

TG 56:9

− 0.256 (− 1.065, 0.553)

0.511

− 0.117 (− 0.34, 0.106)

0.28

TG 58:8

0.112 (− 0.398, 0.622)

0.89

− 0.01 (− 0.155, 0.135)

0.881

TG 58:9

− 0.086 (− 0.628, 0.457)

0.741

− 0.076 (− 0.224, 0.072)

0.289

TG 58:10

0.009 (− 0.649, 0.668)

0.976

− 0.052 (− 0.236, 0.132)

0.553

  1. CI confidence interval, BH Benjamini–Hochberg corrected
  2. aIn mid-gestation 75 g three time-point OGTT
  3. bChange in 13C-DHA lipid with glucose treatment or glucose response (log2-fold-change) represents the relative amount of 13C-DHA lipid in placental explants treated with glucose (10 mmol/L) compared to control explants from the same placenta. Positive values indicate an increase in 13C-DHA lipids compared to the control, whilst negative values indicate a decrease